In the context of GIS and data analysis, reallocate and reclassify are two distinct processes. Reclassification involves changing the assigned values or categories of data based on specific criteria or rules. On the other hand, reallocation refers to the movement of resources or values from one category or class to another. In the field of GIS, reclassification adjustment is a process that allows for changing or adjusting the values or categories of data based on specific criteria or rules.

All osteoporosis patients should be instructed on the importance of calcium and vitamin D supplementation in maintaining serum calcium levels [see DOSAGE AND ADMINISTRATION, ADVERSE REACTIONS, PATIENT INFORMATION]. The incidence of all atrial fibrillation adverse events in the Reclast treatment group was 3.3% (5 out of 153) compared to 2.0% (3 out of 148) in the active control group. However, there were no patients with adjudicated serious adverse events of atrial fibrillation in the Reclast treatment group.

  • The recommended regimen is a 5 mg infusion given once every 2 years intravenously over no less than 15 minutes.
  • Reclast is only part of a complete program of treatment that may also include diet changes and taking calcium and vitamin supplements.
  • The estimated background risk of major birth defects and miscarriage for the indicated populations is unknown.
  • SAP excess was defined as the difference between the measured level and midpoint of normal range.
  • For patients who develop ONJ while on bisphosphonate therapy, dental surgery may exacerbate the condition.

In 64 patients with cancer and bone metastases on average (± SD) 39 ± 16% of the administered zoledronic acid dose was recovered in the urine within 24 hours, with only trace amounts of drug found in urine post Day 2. The cumulative percent of drug excreted in the urine over 0-24 hours was independent of dose. The balance of drug not recovered in urine over 0-24 hours, representing drug presumably bound to bone, is slowly released back into the systemic circulation, giving rise to the observed prolonged low plasma concentrations. In animal studies, less than 3% of the administered intravenous dose was found in the feces, with the balance either recovered in the urine or taken up by bone, indicating that the drug is eliminated intact via the kidney.

What about side effects?

Reclast Injection is available as a sterile solution in bottles for intravenous infusion. One bottle with 100 mL solution contains 5.330 mg of zoledronic acid monohydrate, equivalent to 5 mg zoledronic acid on an anhydrous basis. Reclast may interact with diuretics (water pills), antibiotics, other medicines that can harm your kidneys, cancer medicines, or nonsteroidal anti-inflammatory drugs (NSAIDs).

  • Previous school credits and grade level can be important factors in the reclassification process.
  • Other adverse fetal effects at this dose included reduced lens, rudimentary cerebellum, reduction or absence of liver lobes, reduction of lung lobes, vessel dilation, cleft palate, and edema.
  • Reclast is given as an infusion into a vein by a nurse or a doctor, and the infusion time must not be less than 15 minutes.
  • However, adverse reactions seen more commonly in pediatric patients included pyrexia (61%), arthralgia (26%), hypocalcemia (22%) and headache (22%).
  • The dosage is based on your medical condition and response to treatment.
  • A separate journal entry in your liabilities report should be created for credit balances so you can easily see your liability position and make appropriate adjustments.

Zolendronic acid is given as an infusion (through a vein in your arm) lasting 15 minutes. You should drink 2 glasses of fluid at least one hour before receiving your infusion. You should not take Zolendronic acid if you are pregnant, breast feeding, have kidney problems, or have low blood calcium.

Still, by keeping track of credit balances, you may uncover shoddy accounting practices or a pattern of inaccurate billing in your business office. Ongoing customer relations often leave your clients with a credit balance, meaning they’ve paid you more than their current invoice reflects. As long as the credit balance remains in the accounts receivable column, your clients can order new products or services and use the balance to satisfy their invoices. You should develop a company policy that requires your accountant to report on outstanding credit balances on a regular basis and define a time line as to when you’ll move the funds into the liabilities report. Current liabilities usually include income taxes, accounts payable and future payable accounts as well as short-term loans. provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include Micromedex (updated 2 Jan 2024), Cerner Multum™ (updated 16 Nov 2023), ASHP (updated 10 Jan 2024) and others. Zometa is another brand of zoledronic acid used to treat high blood levels of calcium caused by cancer (also called hypercalcemia of malignancy).

These include an organizational chart, old job descriptions, a comparison of the job with others in the department/unit, and provides a context for understanding the job within the larger organizational structure. First, it ensures that financial statements accurately reflect the true nature of transactions, providing users with a reliable and trustworthy source of information. Second, it ensures compliance with accounting standards and principles, maintaining consistency and comparability across different periods and entities. absorption costing and variable costing explained Third, reclassification promotes transparency and disclosure, allowing stakeholders to understand the reasons behind the reclassification and make informed decisions. When a reclassification is needed, accountants review the original entry and determine whether it was initially recorded incorrectly or if it needs to be reclassified based on new information or account structure changes. The decision to reclassify involves a careful analysis of the transaction’s nature, purpose, and impact on the financial statements.


Drink at least 2 glasses of fluid before treatment unless otherwise directed by your doctor. It is very important that you get plenty of fluids when you are given this medication. Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start using this product and each time you get a refill. Smoking can reduce your bone mineral density, making fractures more likely. This medicine may affect fertility (ability to have children) in women.

What’s the meaning of reclassified?

A single dose of Reclast should not exceed 5 mg and the duration of infusion should be no less than 15 minutes [see DOSAGE AND ADMINISTRATION]. No in vivo drug interaction studies have been performed for Reclast. In vitro and ex vivo studies showed low affinity of zoledronic acid for the cellular components of human blood. In vitro mean zoledronic acid protein binding in human plasma ranged from 28% at 200 ng/mL to 53% at 50 ng/mL. In vivo studies showed that zoledronic acid is not metabolized, and is excreted into the urine as the intact drug.

What should I avoid while receiving Reclast?

Infusion should be followed by a 10 mL normal saline flush of the intravenous line. Rheum.TV is an informational platform created to educate patients living with a rheumatic disease. With over 100 disease education videos produced by the team at Johns Hopkins Rheumatology.

Discover the significance of reclass in accounting and its role in financial management. Explore how reclassifications impact finance and streamline reporting processes. For the treatment of Paget’s disease, this medication is given as a single dose and may be repeated based on your symptoms. For the treatment of osteoporosis, this medication is given as a single dose once a year.

The Ultimate Guide to the Three Financial Statements

In addition, reclassification can help you explore different subjects and open up new career opportunities that may have otherwise been unavailable. There might be special considerations when it comes to taking classes outside your current grade level, so make sure you understand all the expectations before moving forward. You are encouraged to report negative side effects of prescription drugs to the FDA. Some people who take bisphosphonates develop severe bone, joint, or muscle pain. The estimated background risk of major birth defects and miscarriage for the indicated populations is unknown.